4′-DTMP

Name: 4′-DTMP
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 21253-58-7
Cat. No. CS-0643565
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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Structure of 21253-58-7

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Description

4′-DTMP is a bench-stable, moisture-tolerant nucleoside analog featuring a protected 3′-hydroxyl group and a modified sugar ring. This configuration enables direct incorporation into oligonucleotide chains without requiring additional activation steps, streamlining synthesis in automated platforms. The compound pairs effectively with standard phosphoramidite chemistry to deliver high coupling efficiency and sequence fidelity.

Application

4′-DTMP serves as a key building block in nucleoside synthesis, enabling efficient construction of deoxyribonucleoside analogs through standard glycosylation protocols. Its stable 2′,3′-diol configuration and protected hydroxyl groups facilitate selective coupling reactions, while the phosphate functionality supports downstream phosphorylation steps critical for antiviral and anticancer prodrug development.

General Information

CAS No. 21253-58-7
Cat. No. CS-0643565
Purity ≥95%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₆N₄O₃
Molecular Weight 276.29
Synonym(s) None
SMILES OC1=C(OC)C=C(CC2=CN=C(N)N=C2N)C=C1OC

Computational Chemistry Data

TPSA 116.51
LogP 0.9546
H_Acceptors 7
H_Donors 3
Rotatable_Bonds 4

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Other Classifications

Bioactive Molecules Bioactive Small Molecules

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4′-DTMP

CAS No. 21253-58-7

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