2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)acetic acid hydrate

Name: 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)acetic acid hydrate
Brand: ChemScene
Availability: InStock
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CAS No. 212651-47-3
Cat. No. CS-W002481
Purity≥98%
MDL No.MFCD00180724

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)acetic acid hydrate|CS-W002481

Structure of 212651-47-3

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Description

This fluorenylmethoxycarbonyl-protected amino acid derivative features a stable, moisture-tolerant hydrate form and integrates seamlessly into peptide synthesis workflows. The C-terminal carboxyl group enables efficient coupling, while the fluorenylmethoxycarbonyl (Fmoc) moiety ensures high-yield deprotection under mild basic conditions.

Application

2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)acetic acid hydrate serves as a stable, bench-ready carbamate protecting group for amino acids and peptides. It facilitates efficient N-terminal protection in solid-phase peptide synthesis, offering excellent solubility, minimal side reactions, and straightforward deprotection under mild basic conditions. Its robust fluorenylmethoxycarbonyl (Fmoc) backbone ensures high fidelity in sequence assembly and compatibility with diverse functional groups.

General Information

CAS No. 212651-47-3
Cat. No. CS-W002481
Purity ≥98%
MDL No. MFCD00180724
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₈H₁₉NO₅
Molecular Weight None
Synonym(s) None
SMILES O=C(N(CC(O)=O)C)OCC1C2=CC=CC=C2C3=CC=CC=C13.O

Computational Chemistry Data

TPSA 98.34
LogP 2.1272
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 4

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Building Blocks Functional Group Fmoc

Life Science Amino Acids and their Derivatives Glycine and derivatives

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

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2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)acetic acid hydrate

CAS No. 212651-47-3

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