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CS-W001157 4
Total: USD 88.00

2-Ethoxyphenylboronic acid

  • CAS No. 213211-69-9

  • Cat. No. CS-W016068
  • Purity≥98%
  • MDL No.MFCD00674027
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Ethoxyphenylboronic acid|CS-W016068

Structure of 213211-69-9

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Description

2-Ethoxyphenylboronic acid features a boronate moiety attached to an electron-rich phenyl ring, enabling efficient Suzuki-Miyaura cross-coupling reactions. The ethoxy substituent enhances solubility in polar organic solvents and contributes to improved stability under standard handling conditions. This compound serves as a reliable building block for synthesizing functionalized biaryls and complex pharmaceutical intermediates.

Application

2-Ethoxyphenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its ortho-ethoxy substitution enhances solubility and stability compared to unsubstituted analogs, while the boronic acid group exhibits predictable reactivity with aryl halides and triflates. The compound demonstrates good bench stability, facilitates straightforward purification, and functions reliably in the synthesis of biaryl scaffolds relevant to pharmaceutical and materials chemistry.

General Information

  • CAS No. 213211-69-9
  • Cat. No. CS-W016068
  • Purity ≥98%
  • MDL No. MFCD00674027
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BO₃
  • Molecular Weight 165.98
  • Synonym(s) 2-Ethoxybenzeneboronic Acid (contains varying amounts of Anhydride); 2-Ethoxyphenylboronic acid
  • SMILES CCOC1=C(C=CC=C1)B(O)O

Computational Chemistry Data

  • TPSA   49.69
  • LogP   -0.2349
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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