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CS-W001157 4
Total: USD 88.00

3-Isoprophenylboronic acid

  • CAS No. 216019-28-2

  • Cat. No. CS-W020415
  • Molecule weight164.01
  • Purity≥96%
  • MDL No.MFCD01074634

*For research and further manufacturing use only, not for direct human use.

3-Isoprophenylboronic acid|CS-W020415

Structure of 216019-28-2

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General Information

  • CAS No. 216019-28-2
  • Cat. No. CS-W020415
  • Purity ≥96%
  • MDL No. MFCD01074634
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃BO₂
  • Molecular Weight 164.01
  • Synonym(s) 3-isopropylphenylboronicacid
  • SMILES CC(C1=CC(B(O)O)=CC=C1)C

Description

3-Isopropylboronic acid features a boronate moiety flanked by an isopropyl group, delivering enhanced stability and moisture tolerance. This bench-stable reagent integrates efficiently into Suzuki-Miyaura cross-coupling reactions, enabling reliable carbon-carbon bond formation under standard conditions.

Application

3-Isopropylphenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures under mild conditions. Its stability, ease of handling, and tolerance to diverse functional groups make it well-suited for the synthesis of pharmaceutical intermediates and functional materials.

Synthesis

  • Route1
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      5419-55-6
    • In-stock
      1-Bromo-3-isopropylbenzene|CS-W010514
      5433-01-2
    • ~%
    • In-stock
      3-Isoprophenylboronic acid|CS-W020415
      216019-28-2

    References

    • US2010/41713 A1, ; Page/Page column 19-20 ; US 20100041713 A1
  • Route2

    References

    • Mazzanti, Andrea; Lunazzi, Lodovico; Minzoni, Mirko; Anderson, J. Edgar Journal of Organic Chemistry, 2006 , vol. 71, # 15 p. 5474 - 5481

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.4898
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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