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Structure of 2138507-91-0
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1-Cyclobutylpropan-1-amine (hydrochloride) features a rigid cyclobutyl ring fused to a propan-1-amine backbone, delivering enhanced conformational control. The hydrochloride salt form ensures high solubility and stability under standard conditions, facilitating efficient incorporation into medicinal chemistry campaigns. This scaffold enables precise spatial orientation in target-directed ligand design.
1-Cyclobutylpropan-1-amine (hydrochloride) serves as a versatile bifunctional building block in medicinal chemistry, enabling the construction of bioactive scaffolds through amine-directed functionalization. The cyclobutyl ring imparts conformational rigidity and enhanced metabolic stability, while the primary amine functionality facilitates straightforward derivatization via alkylation, acylation, or reductive amination. Its hydrochloride salt form ensures excellent bench stability, ease of handling, and compatibility with standard purification protocols, making it well-suited for high-throughput synthesis and lead optimization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: