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Structure of 21397-08-0
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2-Chloro-3-fluoroaniline features a strategically positioned chlorine and fluorine substituent on the aromatic ring, delivering enhanced electron-withdrawing character and improved metabolic stability. This ortho-substituted aniline integrates readily into pharmaceutical intermediates and agrochemical scaffolds, offering superior reactivity in coupling processes under standard conditions.
2-Chloro-3-fluoroaniline serves as a valuable building block in the synthesis of pharmaceutical intermediates and agrochemicals, leveraging its ortho-halogenated aniline framework for subsequent Suzuki-Miyaura, Buchwald-Hartwig, or electrophilic substitution reactions. The molecule exhibits good bench stability and facilitates efficient functionalization due to complementary reactivity between chlorine and fluorine substituents. Its utility in constructing complex heterocyclic scaffolds is well-documented in industrial process chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: