Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(4-(tert-Butyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

  • CAS No. 214360-66-4

  • Cat. No. CS-0097791
  • Purity≥97%
  • MDL No.MFCD05663843

*For research and further manufacturing use only, not for direct human use.

2-(4-(tert-Butyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0097791

Structure of 214360-66-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 214360-66-4
  • Cat. No. CS-0097791
  • Purity ≥97%
  • MDL No. MFCD05663843
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₅BO₂
  • Molecular Weight 260.18
  • Synonym(s) 4-Tert-Butylphenylboronic Acid,Pinacol Ester
  • SMILES CC1(C(C)(OB(O1)C2=CC=C(C=C2)C(C)(C)C)C)C

Description

This boronate ester features a sterically shielded tert-butyl-substituted aryl group, enhancing stability and resistance to protodeboronation. It integrates readily into Suzuki-Miyaura cross-coupling reactions under mild conditions, delivering high yields with minimal side product formation. The tetramethyl-substituted dioxaborolane ring ensures excellent shelf life and moisture tolerance during handling.

Application

2-(4-(tert-Butyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. Its sterically protected arylboronate functionality enables reliable coupling with diverse aryl and vinyl halides under mild conditions. The tert-butyl group enhances solubility and stability, while the tetramethyl substituents minimize protodeboronation, facilitating purification and scalable synthesis of biaryl architectures.

Synthesis

  • Route1
    • In-stock
      1-Bromo-4-tert-butylbenzene|CS-W008710
      3972-65-4
    • null|null
      61676-62-8
    • ~97%
    • In-stock
      2-(4-(tert-Butyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0097791
      214360-66-4

    References

    • Molecular Crystals and Liquid Crystals, , vol. 471, # 1 p. 89 - 98
  • Route2

    References

    • Organic Letters, , vol. 13, # 21 p. 5766 - 5769
  • Route3
    • null|null
      1319748-01-0
    • In-stock
      Bis(pinacolato)diborane|CS-D1216
      73183-34-3
    • ~69%
    • In-stock
      2-(4-(tert-Butyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0097791
      214360-66-4

    References

    • Organic Letters, , vol. 14, # 17 p. 4560 - 4563

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   18.46
  • LogP   3.2833
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 214360-66-4 sigma214360-66-4 manufacturer214360-66-4 price214360-66-4 structure214360-66-4 SDSbuy 214360-66-4214360-66-4 supplier214360-66-4 uses214360-66-4 molecular weightprice of 214360-66-4214360-66-4 chemical name formula of 214360-66-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label