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Structure of 2148-56-3
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2-Amino-6-chlorobenzoic acid features a chlorinated aromatic ring with strategically positioned amino and carboxylic acid groups, enabling direct integration into pharmaceutical intermediates. The electron-withdrawing chlorine enhances reactivity at the ortho position, while the amino group facilitates coupling reactions under mild conditions. This scaffold offers high stability and solubility in polar solvents, streamlining synthesis workflows in medicinal chemistry.
2-Amino-6-chlorobenzoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through amidation, cyclization, and electrophilic substitution reactions. Its ortho-amino and chloro substituents provide complementary reactivity for sequential functionalization, while the carboxylic acid facilitates direct coupling or derivatization. Bench-stable and readily purified by recrystallization, it functions efficiently in standard synthetic workflows for API intermediates and bioactive molecule development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: