3-Bromo-2-chloropyridin-4-amine

Name: 3-Bromo-2-chloropyridin-4-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 215364-85-5
Cat. No. CS-W015259
Purity≥97%
MDL No.MFCD09263478

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Bromo-2-chloropyridin-4-amine|CS-W015259

Structure of 215364-85-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 215364-85-5
Cat. No. CS-W015259
Purity ≥97%
MDL No. MFCD09263478
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₄BrClN₂
Molecular Weight 207.46
Synonym(s) 4-pyridinamine, 3-bromo-2-chloro-
SMILES ClC1=NC=CC(N)=C1Br

Description

3-Bromo-2-chloropyridin-4-amine features a pyridine core functionalized with bromo and chloro substituents at the 3- and 2-positions, respectively, and an amine group at the 4-position. This electron-deficient heterocycle serves as a key building block in medicinal chemistry, enabling direct coupling reactions via its amine handle. The dual halogenation pattern supports sequential cross-coupling strategies in target diversification.

Application

3-Bromo-2-chloropyridin-4-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromo group facilitates efficient Suzuki, Stille, or Negishi couplings, while the chloro and amino functionalities provide sites for further functionalization. Its bench-stable nature and compatibility with standard synthetic protocols make it ideal for constructing complex heterocyclic scaffolds in API development.

Synthesis

Route1
- In-stock
  
  14432-12-3
- ~%
- In-stock
  
  215364-85-5
References
- WO2008/124083 A2, ; Page/Page column 47 ; WO 2008/124083 A2
Route2
- In-stock
  
  14432-12-3
- ~%
- In-stock
  
  857730-21-3
- In-stock
  
  215364-85-5
References
- WO2005/61500 A1, ; Page/Page column 158 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 38.91
LogP 2.0797
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

3-Bromo-2-chloropyridin-4-amine sigma3-Bromo-2-chloropyridin-4-amine manufacturer3-Bromo-2-chloropyridin-4-amine price3-Bromo-2-chloropyridin-4-amine structure3-Bromo-2-chloropyridin-4-amine SDSbuy 3-Bromo-2-chloropyridin-4-amine3-Bromo-2-chloropyridin-4-amine supplier3-Bromo-2-chloropyridin-4-amine uses3-Bromo-2-chloropyridin-4-amine molecular weightprice of 3-Bromo-2-chloropyridin-4-amine3-Bromo-2-chloropyridin-4-amine chemical name formula of 3-Bromo-2-chloropyridin-4-amine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

3-Bromo-2-chloropyridin-4-amine

CAS No. 215364-85-5

Recommended Products