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Structure of 216976-31-7
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3-Fluoro-5-methylphenol features a fluorine atom at the meta position and a methyl group at the para position relative to the phenolic hydroxyl, creating a uniquely activated aromatic system. This electron-deficient yet sterically accessible scaffold integrates readily into synthetic routes requiring polarized aryl coupling partners. The compound exhibits enhanced stability under standard bench conditions and demonstrates favorable solubility in common organic solvents, facilitating its use in pharmaceutical intermediates and agrochemical development.
3-Fluoro-5-methylphenol serves as a valuable building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds via standard coupling reactions. Its ortho-fluoro and meta-methyl substituents provide directed functionalization potential and enhanced metabolic stability. The compound exhibits good bench stability and facilitates efficient derivatization for API development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H314-H318
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Precautionary Statements : P280-P304+P340
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Lot numbers can be found on the outside label of a product: