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Structure of 74-69-1
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2-Methyl-4-pyrimidinamine is a bench-stable heterocyclic amine featuring a pyrimidine core with methyl and amino substituents at the 2- and 4-positions, respectively. This configuration imparts enhanced solubility in polar solvents and facilitates direct incorporation into medicinal chemistry scaffolds. The compound serves as a key intermediate in the synthesis of kinase inhibitors and nucleoside analogs due to its reactive nitrogen sites and favorable electronic profile.
2-Methyl-4-pyrimidinamine serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrimidine-based scaffolds. Its amino functionality facilitates nucleophilic substitution and coupling reactions, while the methyl group enhances metabolic stability. The compound exhibits good bench stability and compatibility with standard synthetic protocols, making it valuable for the construction of kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: