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CS-W001157 4
Total: USD 88.00

5-Bromo-2-iodobenzoic acid

  • CAS No. 21740-00-1

  • Cat. No. CS-W002338
  • Purity≥98%
  • MDL No.MFCD00079717
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-iodobenzoic acid|CS-W002338

Structure of 21740-00-1

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Description

5-Bromo-2-iodobenzoic acid features a benzoic acid core functionalized with bromo and iodo substituents at the meta and ortho positions, respectively. This dual halogenation enables efficient cross-coupling transformations in synthetic routes. The carboxylic acid group facilitates derivatization and incorporation into bioactive scaffolds. Designed for use in medicinal chemistry and materials synthesis, this compound offers high reactivity under standard palladium-catalyzed conditions.

Application

5-Bromo-2-iodobenzoic acid serves as a versatile dihalogenated aromatic building block for palladium-catalyzed cross-coupling reactions. The bromo and iodo groups enable sequential functionalization via orthogonal reactivity, facilitating the assembly of complex biaryl architectures. Its carboxylic acid functionality offers direct handle for derivatization, while maintaining bench stability and compatibility with standard purification protocols in medicinal chemistry and materials synthesis workflows.

General Information

  • CAS No. 21740-00-1
  • Cat. No. CS-W002338
  • Purity ≥98%
  • MDL No. MFCD00079717
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrIO₂
  • Molecular Weight 326.91
  • Synonym(s) None
  • SMILES BrC1=CC(C(O)=O)=C(I)C=C1

Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.7519
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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