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Structure of 398489-26-4
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tert-Butyl 3-oxoazetidine-1-carboxylate features a strained azetidine ring with a carbonyl at the 3-position, enabling direct functionalization at the C3 carbon. The tert-butyl ester group provides stability and ease of removal under mild acidic conditions. This scaffold serves as a key building block for synthesizing bioactive molecules in medicinal chemistry.
tert-Butyl 3-oxoazetidine-1-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling the construction of azetidine-containing scaffolds prevalent in medicinal chemistry. The ketone functionality facilitates nucleophilic addition and enolate formation, while the tert-butyl ester group offers stability and ease of removal under mild acidic conditions. Its reactivity profile supports diverse transformations including reductive amination, conjugate addition, and ring expansion, making it a practical intermediate for the synthesis of bioactive heterocycles and API candidates.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3335
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: