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Structure of 21778-81-4
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5-Methoxy-1H-indole-2-carbaldehyde features a strategically positioned aldehyde group at the 2-position and a methoxy substituent at the 5-position, enabling direct functionalization in heterocyclic synthesis. This electron-rich indole scaffold offers enhanced solubility and stability under standard conditions, facilitating its use in medicinal chemistry and materials science applications.
5-Methoxy-1H-indole-2-carbaldehyde serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient access to indole-based scaffolds. Its aldehyde functionality facilitates reductive amination, Grignard additions, and Ugi-type reactions, while the methoxy group enhances solubility and modulates electronic properties. Bench-stable and readily purified by column chromatography, it functions reliably in multi-step syntheses requiring orthogonality and functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: