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Structure of 4792-58-9
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Ethyl 5-methoxy-1H-indole-2-carboxylate features a bench-stable indole core with a strategically positioned methoxy group at the 5-position, enhancing electron density at C5. The ester functionality at C2 enables direct integration into coupling reactions, facilitating rapid access to substituted indole architectures in medicinal chemistry and materials synthesis.
Ethyl 5-methoxy-1H-indole-2-carboxylate serves as a versatile building block for indole-based scaffolds, enabling efficient access to functionalized heterocycles via palladium-catalyzed cross-coupling and electrophilic substitution. The ethyl ester group facilitates downstream derivatization, while the 5-methoxy substituent enhances solubility and modulates reactivity. Bench-stable and readily purified by column chromatography, it functions effectively in medicinal chemistry and API intermediate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: