(S)-Ethyl 2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoate

Name: (S)-Ethyl 2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 21959-36-4
Cat. No. CS-0186190
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(S)-Ethyl 2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoate|CS-0186190

Structure of 21959-36-4

Size

Price

Quantity

* Please select Quantity before adding items.

Description

(S)-Ethyl 2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoate features a chiral center at the alpha carbon, enabling stereoselective synthesis in medicinal chemistry. The para-hydroxyl and diiodo substitution pattern on the aromatic ring imparts high electron density and enhanced metabolic stability. This configuration supports efficient coupling reactions under standard conditions, facilitating access to complex peptide-like architectures.

Application

(S)-Ethyl 2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoate serves as a key chiral building block for the synthesis of bioactive heterocycles and peptide-like scaffolds. Its pendant phenolic hydroxyl group enables facile derivatization, while the diiodophenyl moiety supports palladium-catalyzed cross-coupling reactions. The molecule exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthetic campaigns in medicinal chemistry and process development.

General Information

CAS No. 21959-36-4
Cat. No. CS-0186190
Purity ≥98%
MDL No. None
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₅I₂NO₄
Molecular Weight 503.07
Synonym(s) N-Acetyl-3,5-diiodo-l-tyrosine ethyl ester
SMILES CCOC([C@@H](NC(C)=O)CC1=CC(I)=C(O)C(I)=C1)=O

Computational Chemistry Data

TPSA 75.63
LogP 2.2117
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 5

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301-H319
Precautionary Statements : P305+P351+P338

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Phenol

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Tyrosine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Key Words

21959-36-4 sigma21959-36-4 manufacturer21959-36-4 price21959-36-4 structure21959-36-4 SDSbuy 21959-36-421959-36-4 supplier21959-36-4 uses21959-36-4 molecular weightprice of 21959-36-421959-36-4 chemical name formula of 21959-36-4

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(S)-Ethyl 2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoate

CAS No. 21959-36-4

Recommended Products