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Structure of 220227-47-4
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4-Fluoro-3-(trifluoromethyl)phenylacetic acid features a fluorinated aromatic ring paired with a trifluoromethyl group, delivering enhanced metabolic stability and lipophilicity. This electron-deficient arylacetic acid integrates readily into bioactive scaffolds, serving as a key building block in medicinal chemistry for targeted kinase inhibitors and CNS-active compounds.
4-Fluoro-3-(trifluoromethyl)phenylacetic acid serves as a valuable building block for bioactive molecule synthesis, offering enhanced metabolic stability and lipophilicity due to the combined electron-withdrawing effects of the fluorine and trifluoromethyl groups. Its carboxylic acid functionality enables direct derivatization or coupling reactions, while the aryl side chain exhibits robust bench stability and compatibility with standard synthetic protocols, facilitating efficient access to pharmaceutical intermediates and functionalized heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P302+P352
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Lot numbers can be found on the outside label of a product: