(R)-Methyl 2-amino-3-(1H-indol-3-yl)propanoate

Name: (R)-Methyl 2-amino-3-(1H-indol-3-yl)propanoate
Brand: ChemScene
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CAS No. 22032-65-1
Cat. No. CS-0150948
Purity≥97%
MDL No.MFCD08669786

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(R)-Methyl 2-amino-3-(1H-indol-3-yl)propanoate|CS-0150948

Structure of 22032-65-1

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Description

(R)-Methyl 2-amino-3-(1H-indol-3-yl)propanoate features a chiral α-amino acid scaffold fused to an indole moiety, enabling direct incorporation into peptide-based drug candidates. The molecule exhibits bench-stable handling characteristics and facilitates efficient coupling reactions under standard conditions.

Application

(R)-Methyl 2-amino-3-(1H-indol-3-yl)propanoate serves as a valuable chiral building block for the synthesis of indole-containing bioactive molecules. Its pendant amine and ester functionalities enable selective derivatization, while the (R)-configuration ensures stereochemical fidelity in downstream applications. The compound exhibits good bench stability and facilitates efficient incorporation into peptide-like scaffolds and heterocyclic frameworks relevant to medicinal chemistry research.

General Information

CAS No. 22032-65-1
Cat. No. CS-0150948
Purity ≥97%
MDL No. MFCD08669786
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₁₄N₂O₂
Molecular Weight 218.25
Synonym(s) Methyl D-tryptophanate
SMILES COC(=O)[C@@H](CC1=CNC2=CC=CC=C12)N

Computational Chemistry Data

TPSA 68.11
LogP 1.2107
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Indole compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Tryptophan and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids C-ProtectedAmino Acids

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(R)-Methyl 2-amino-3-(1H-indol-3-yl)propanoate

CAS No. 22032-65-1

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