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Structure of 220801-66-1
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Methyl 2-(5-bromo-2-hydroxyphenyl)acetate features a brominated phenolic scaffold with a pendant ester group, enabling direct functionalization in cross-coupling and derivatization workflows. The hydroxyl moiety offers sites for further modification, while the methyl ester facilitates selective transformations under mild conditions. This compound demonstrates excellent stability and solubility in common organic solvents, streamlining its integration into synthetic sequences for pharmaceutical intermediates and advanced materials.
Methyl 2-(5-bromo-2-hydroxyphenyl)acetate serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. The bromo and hydroxyl groups enable sequential functionalization via palladium-catalyzed coupling and directed ortho-metalation, while the ester moiety supports further transformations. Bench-stable and readily purified by column chromatography, it functions efficiently in standard cross-coupling and cyclization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: