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Structure of 22090-26-2
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1-(4-Bromophenyl)pyrrolidine features a brominated aromatic ring linked to a pyrrolidine heterocycle, delivering enhanced electron-withdrawing character and structural rigidity. This combination enables efficient incorporation into pharmaceutical scaffolds, particularly in kinase inhibitor designs and bioactive compound libraries. The molecule exhibits favorable solubility profiles and stability under standard handling conditions.
1-(4-Bromophenyl)pyrrolidine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through palladium-catalyzed cross-coupling reactions. Its brominated aryl group facilitates efficient Suzuki, Stille, and Negishi couplings, while the pyrrolidine moiety provides a basic nitrogen for salt formation and hydrogen bonding. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: