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Structure of 220901-25-7
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This brominated benzoic acid derivative features a methoxy group at the 6-position and a methyl substituent at the 2-position, creating a sterically hindered, electron-rich aromatic core. The strategically positioned bromine enables efficient cross-coupling reactions, while the carboxylic acid functionality facilitates direct derivatization. This compound serves as a modular building block for bioactive molecule synthesis under standard conditions.
3-Bromo-6-methoxy-2-methylbenzoic acid serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling direct incorporation into biaryl and heterocyclic scaffolds via palladium-catalyzed coupling reactions. The ortho-methyl and methoxy groups provide steric and electronic modulation, while the bromo and carboxylic acid functionalities offer complementary reactivity for late-stage functionalization. Bench-stable and readily purified by recrystallization, it functions efficiently in standard cross-coupling, amidation, and esterification protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: