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Structure of 221220-99-1
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3-Bromo-2,6-difluorophenol features a bromine substituent flanked by two fluorine atoms on the aromatic ring, delivering enhanced electron-withdrawal and improved metabolic stability. This trifunctional phenol integrates readily into complex synthetic sequences, particularly in medicinal chemistry and agrochemical development, where halogen-directed coupling reactions are required.
3-Bromo-2,6-difluorophenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling site-selective functionalization via palladium-catalyzed cross-coupling reactions. The ortho-fluoro substituents enhance electrophilic reactivity while maintaining bench stability, and the phenolic hydroxyl group facilitates derivatization or protection strategies. Its defined substitution pattern supports predictable regiochemistry in heterocycle formation and transition-metal-mediated transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: