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Structure of 221538-03-0
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This tert-butyl carbamate derivative features a brominated methyl-substituted phenyl scaffold, enabling direct incorporation into cross-coupling and functionalization workflows. The robust protecting group remains stable under standard reaction conditions while allowing selective deprotection to reveal the primary amine.
(3-Bromo-2-methyl-phenyl)-carbamic acid tert-butyl ester serves as a stable, bench-ready building block for the synthesis of substituted anilines and heterocyclic scaffolds. The tert-butyl carbamate group enables facile deprotection under mild acidic conditions, while the ortho-bromo and meta-methyl substituents provide orthogonal reactivity for palladium-catalyzed cross-coupling and directed functionalization. Its compatibility with standard synthetic workflows makes it a practical choice for medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: