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Structure of 55589-47-4
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3-Methylpyridine-2-carboxaldehyde features a pyridine ring bearing a methyl group at the 3-position and an aldehyde functionality at the 2-position, creating a rigid, electron-deficient heteroaromatic scaffold. This configuration enables direct integration into transition metal-catalyzed coupling reactions and facilitates coordination in ligand design for catalytic systems requiring strong π-acidity. The aldehyde group remains stable under standard handling conditions, allowing straightforward derivatization via imine formation or reductive amination.
3-Methylpyridine-2-carboxaldehyde serves as a versatile building block in synthetic organic chemistry, enabling the construction of bioactive heterocycles and pharmaceutical intermediates. Its ortho-aldehyde functionality facilitates efficient imine formation, Mannich reactions, and transition-metal-catalyzed couplings. The methyl group enhances regioselectivity in electrophilic substitutions, while the aldehyde remains stable under standard bench conditions, allowing straightforward handling and purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H302-H315-H319-H335
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Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: