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Structure of 22191-97-5
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Binding selectively to aggregated tau filaments with high affinity (EC50: 221 nM), BF-170 hydrochloride (CAS 22191-97-5) achieves rapid brain penetration—9.1% ID/g within 2 min post-i.v. in mice—and exhibits sustained retention, enabling non-invasive imaging of tau pathology in early Alzheimer’s disease models.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: