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1-(5-Aminopentyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate

  • CAS No. 222159-87-7

  • Cat. No. CS-0158354
  • Molecule weight296.24
  • Purity≥98%
  • MDL No.MFCD01073616

*For research and further manufacturing use only, not for direct human use.

1-(5-Aminopentyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate|CS-0158354

Structure of 222159-87-7

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General Information

  • CAS No. 222159-87-7
  • Cat. No. CS-0158354
  • Purity ≥98%
  • MDL No. MFCD01073616
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₅F₃N₂O₄
  • Molecular Weight 296.24
  • Synonym(s) N-(5-Aminopentyl)maleimide Trifluoroacetic Acid Salt
  • SMILES C(CCN)CCN1C(=O)C=CC1=O.C(=O)(C(F)(F)F)O

Description

1-(5-Aminopentyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate features a flexible aliphatic amine tether linked to a pyrrolinedione core, enhancing solubility and reactivity in synthetic transformations. The trifluoroacetate counterion improves handling and compatibility in aqueous and organic media, enabling efficient conjugation and derivatization under standard conditions.

Application

1-(5-Aminopentyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate serves as a versatile bifunctional building block, enabling efficient conjugation and derivatization in synthetic peptide and small molecule chemistry. The primary amine facilitates nucleophilic reactions, while the pyrroledione core provides structural rigidity and hydrogen-bonding capacity. The trifluoroacetate salt enhances solubility and stability during storage and handling, supporting straightforward purification and integration into diverse synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   100.7
  • LogP   0.6737
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   5

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