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*For research and further manufacturing use only, not for direct human use.
Structure of 2225940-46-3
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Pomalidomide-C2-acid features a C2-carboxylic acid functionalization that enhances solubility and reactivity for conjugation workflows. This derivative enables site-specific bioconjugation in targeted protein therapeutics, offering improved stability and compatibility with aqueous reaction conditions.
Pomalidomide-C2-acid serves as a key synthetic intermediate for derivatization of the imidazolone core in pomalidomide-based therapeutics. Its C2-carboxylic acid functionality enables direct amidation, esterification, or coupling reactions under standard peptide synthesis conditions, facilitating rapid access to analogs for structure-activity studies. The compound exhibits good bench stability and is compatible with common purification methods, supporting efficient route development in medicinal chemistry campaigns targeting immunomodulatory agents.
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GHS Pictogram :
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GHS No : GHS08
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H361
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Precautionary Statements : P280-P405-P501
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Lot numbers can be found on the outside label of a product: