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Structure of 2227-57-8
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This propargylic acid features a para-methoxyphenyl group that enhances solubility and modulates electronic properties. The terminal alkyne enables efficient coupling in copper-catalyzed reactions, while the carboxylic acid facilitates conjugation or derivatization under standard conditions.
3-(4-Methoxyphenyl)prop-2-ynoic acid serves as a versatile building block for the synthesis of conjugated enynes and heterocyclic systems. Its terminal alkyne functionality enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the para-methoxyaryl group provides electronic stabilization and enhanced solubility. The carboxylic acid moiety facilitates direct derivatization or activation for amide bond formation, offering robust utility in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: