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Structure of 223671-15-6
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7-Bromoisoquinolin-1-ol features a bromine substituent at the 7-position of the isoquinoline core, enabling direct functionalization in cross-coupling reactions. The phenolic hydroxyl group provides a handle for derivatization and enhances solubility in polar solvents. This scaffold combines electron-deficient aromatic character with a reactive site, making it valuable for synthesizing bioactive molecules and advanced ligands in catalysis.
7-Bromoisoquinolin-1-ol serves as a versatile building block for the synthesis of isoquinoline-based scaffolds, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromine handle. The phenolic hydroxyl group provides a site for derivatization or protection, enhancing functional group tolerance in multi-step syntheses. Its bench-stable solid form facilitates handling and purification, making it suitable for medicinal chemistry campaigns and process development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: