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(S)-2-Amino-2-(2,4-difluorophenyl)ethan-1-ol hydrochloride

  • CAS No. 2241594-36-3

  • Cat. No. CS-0095548
  • Molecule weight209.62
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-2-Amino-2-(2,4-difluorophenyl)ethan-1-ol hydrochloride|CS-0095548

Structure of 2241594-36-3

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General Information

  • CAS No. 2241594-36-3
  • Cat. No. CS-0095548
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀ClF₂NO
  • Molecular Weight 209.62
  • Synonym(s) (S)-2-Amino-2-(2,4-difluorophenyl)ethanol hydrochloride
  • SMILES OC[C@@H](N)C1=CC=C(F)C=C1F.[H]Cl

Description

(S)-2-Amino-2-(2,4-difluorophenyl)ethan-1-ol hydrochloride features a chiral α-amino alcohol scaffold with dual fluorine substituents that enhance metabolic stability and membrane permeability. This bench-stable crystalline salt integrates readily into asymmetric synthesis workflows, serving as a key building block for bioactive molecules in medicinal chemistry.

Application

(S)-2-Amino-2-(2,4-difluorophenyl)ethan-1-ol hydrochloride serves as a key chiral building block for bioactive molecules, enabling efficient access to pharmaceutically relevant scaffolds. Its well-defined stereochemistry and functional group tolerance facilitate straightforward incorporation into peptide-like structures and heterocyclic systems. The hydrochloride salt enhances solubility and stability, supporting reliable handling in synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   1.3787
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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