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Structure of 2245238-80-4
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Lithium 4,6-dichloropyridazine-3-carboxylate features a dual chloro substitution at the 4- and 6-positions of the pyridazine ring, enhancing electrophilic reactivity at the 3-carboxylate site. This bench-stable lithium salt facilitates direct coupling reactions in late-stage functionalization, enabling efficient access to diverse heterocyclic scaffolds under mild conditions.
Lithium 4,6-dichloropyridazine-3-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the C3 position via nucleophilic substitution. The dichloro substitution pattern provides orthogonal reactivity for sequential coupling, while the lithium carboxylate facilitates smooth transmetalation and subsequent transformations. Its bench-stable nature and compatibility with standard cross-coupling protocols make it ideal for constructing complex pyridazine-based scaffolds in medicinal chemistry and agrochemical research.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: