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Structure of 84955-31-7
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6-Chloro-7-deazaguanine is a purine analog featuring a chlorine substituent at the 6-position and a nitrogen-to-carbon substitution at the 7-position, enhancing metabolic stability. This structural modification improves resistance to enzymatic degradation while maintaining base-pairing fidelity, making it valuable for nucleoside analog synthesis in antiviral and anticancer research.
6-Chloro-7-deazaguanine serves as a valuable purine scaffold for medicinal chemistry and nucleoside analog synthesis, offering enhanced metabolic stability and tunable base-pairing properties. Its chloro substitution at the C6 position enables selective derivatization in late-stage functionalization, while the 7-deaza modification improves resistance to enzymatic degradation. The compound exhibits good bench stability and facilitates efficient incorporation into oligonucleotides and antiviral prodrug candidates through standard coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: