Lot numbers can be found on the outside label of a product:
2-Methoxynaphthalen-1-amine
-
CAS No. 2246-42-6
- Cat. No. CS-0237387
- Purity≥96%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 2246-42-6
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 2246-42-6
- Cat. No. CS-0237387
- Purity ≥96%
- MDL No. None
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₁H₁₁NO
- Molecular Weight 173.21
- Synonym(s) 2-methoxynaphthylamine
- SMILES COC1=C(C2=CC=CC=C2C=C1)N
Description
2-Methoxynaphthalen-1-amine features a naphthalene core with strategically positioned methoxy and primary amine groups, enabling versatile integration into pharmaceutical intermediates and functional materials. The electron-donating methoxy substituent enhances reactivity at the adjacent aromatic ring, while the amine moiety facilitates coupling reactions. This compound exhibits good stability under standard handling conditions and serves as a key building block in synthetic routes requiring dual functionalization.
Application
2-Methoxynaphthalen-1-amine serves as a versatile building block in medicinal chemistry and materials science, offering a rigid naphthalene scaffold with orthogonal functional handles. The aniline group enables direct coupling reactions (e.g., Suzuki, Ullmann), while the methoxy substituent enhances solubility and modulates electronic properties. Its bench-stable nature and compatibility with standard purification methods make it well-suited for multi-step synthesis of heterocyclic compounds and API intermediates.
Synthesis
-
Route1
-
In-stock
4900-66-7 - ~93%
-
In-stock
2246-42-6
References
-
Oh, Soo-Jin; Hwang, Seok Jin; Jung, Jonghoon; Yu, Kuai; Kim, Jeongyeon; Choi, Jung Yoon; Hartzell, H. Criss; Roh, Eun Joo; Justin Lee Molecular Pharmacology, 2013 , vol. 84, # 5 p. 726 - 735
-
-
References
-
Syntex Corporation Patent: US3960957 A1, 1976 ;
-
-
Route3
-
In-stock
3401-47-6 - ~70%
-
In-stock
2246-42-6
References
-
Messaoudi, Samir; Brion, Jean-Daniel; Alami, Mouad Advanced Synthesis and Catalysis, 2010 , vol. 352, # 10 p. 1677 - 1687
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 35.25
- LogP 2.4306
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2-Methoxynaphthalen-1-amine sigma2-Methoxynaphthalen-1-amine manufacturer2-Methoxynaphthalen-1-amine price2-Methoxynaphthalen-1-amine structure2-Methoxynaphthalen-1-amine SDSbuy 2-Methoxynaphthalen-1-amine2-Methoxynaphthalen-1-amine supplier2-Methoxynaphthalen-1-amine uses2-Methoxynaphthalen-1-amine molecular weightprice of 2-Methoxynaphthalen-1-amine2-Methoxynaphthalen-1-amine chemical name formula of 2-Methoxynaphthalen-1-amine