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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-5-methylhexanoic acid

  • CAS No. 2260800-15-3

  • Cat. No. CS-0312201
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-5-methylhexanoic acid|CS-0312201

Structure of 2260800-15-3

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General Information

  • CAS No. 2260800-15-3
  • Cat. No. CS-0312201
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₂₇NO₄
  • Molecular Weight 381.46
  • Synonym(s) Fmoc-N-Me-L-HomoLeu-OH
  • SMILES CC(C)CC[C@@H](C(O)=O)N(C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C

Description

This fluorenylmethoxycarbonyl-protected amino acid derivative features a chiral side chain with a methyl substituent, enabling selective incorporation into peptide sequences. The C-terminal carboxylic acid group supports efficient coupling reactions, while the Fmoc moiety ensures stable storage and orthogonal deprotection under mild basic conditions.

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-5-methylhexanoic acid serves as a robust chiral building block for peptide synthesis, enabling efficient incorporation of sterically hindered, branched side chains. The Fmoc-protected amine and pendant methyl group offer enhanced solubility and stability during coupling reactions, while the C5-methyl substituent provides defined stereochemical control. Its bench-stable nature and compatibility with standard SPPS protocols facilitate reliable synthesis of complex peptides and peptidomimetics.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   4.7567
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   7

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