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Structure of 2287228-20-8
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This boronate moiety integrates a trifluoromethyl group at the pyrazole C4 position, enhancing electron deficiency and metabolic stability. The ethyl substituent at N1 improves solubility and reduces aggregation. Designed for efficient Suzuki-Miyaura coupling under standard conditions, this bench-stable reagent enables rapid access to fluorinated heteroaryl architectures in medicinal chemistry and materials synthesis.
(1-Ethyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)boronic acid serves as a stable, bench-ready building block for Suzuki-Miyaura cross-coupling reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the pyrazole core provides a rigid, polar scaffold suitable for medicinal chemistry applications. The boronic acid functionality enables efficient coupling with aryl and heteroaryl halides under mild conditions, offering high functional group tolerance and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: