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Structure of 22918-03-2
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4-Chloro-2-iodopyridine is a halogenated pyridine derivative featuring complementary reactive sites for cross-coupling and functionalization. The chlorine at the 4-position enables palladium-catalyzed coupling, while the iodine at the 2-position offers high reactivity in Suzuki, Stille, or Negishi reactions. This dual functionality supports efficient access to substituted pyridine scaffolds in medicinal chemistry and materials synthesis.
4-Chloro-2-iodopyridine serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient C–C and C–heteroatom bond formation. The ortho-iodo group facilitates palladium-catalyzed coupling with high regioselectivity, while the para-chloro substituent offers complementary reactivity for sequential functionalization. Its bench-stable crystalline form enables straightforward handling, purification, and integration into multi-step syntheses of heterocyclic scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: