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Structure of 456-24-6
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2-Fluoro-5-nitropyridine features a fluorine atom at the 2-position and a nitro group at the 5-position on a pyridine ring, creating a highly electron-deficient heterocycle. This arrangement enables selective coupling reactions in synthetic chemistry, particularly in cross-coupling and nucleophilic substitution processes. The compound exhibits bench-stable handling characteristics and compatibility with diverse reaction conditions.
2-Fluoro-5-nitropyridine serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the C2 position via nucleophilic substitution due to the ortho-fluorine’s reactivity. The nitro group at C5 provides strong electron-withdrawing character, facilitating subsequent transformations such as reduction to an amine or participation in coupling reactions. Its bench-stable nature and compatibility with diverse reaction conditions make it valuable for constructing heterocyclic scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: