2-Bromo-1,1-difluorocyclopentane

Name: 2-Bromo-1,1-difluorocyclopentane
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 2303705-25-9
Cat. No. CS-0377806
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2-Bromo-1,1-difluorocyclopentane|CS-0377806

Structure of 2303705-25-9

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Description

2-Bromo-1,1-difluorocyclopentane is a fluorinated cyclopentane derivative featuring bromine and two fluorine atoms at adjacent ring positions. This configuration imparts high polarity and enhanced metabolic stability, enabling its use in synthetic routes to bioactive molecules. The compound serves as a key building block for pharmaceutical intermediates and specialty materials where controlled reactivity and stereochemical integrity are essential.

Application

2-Bromo-1,1-difluorocyclopentane serves as a versatile fluorinated building block for medicinal chemistry and agrochemical synthesis. Its constrained cyclopentane core supports stereoselective transformations, while the geminal difluoro and bromo substituents enable palladium-catalyzed cross-coupling and subsequent functionalization. The molecule exhibits good bench stability and facilitates access to fluorinated heterocycles and bioactive scaffolds via standard synthetic protocols.

General Information

CAS No. 2303705-25-9
Cat. No. CS-0377806
Purity ≥97%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₇BrF₂
Molecular Weight 185.01
Synonym(s) None
SMILES FC1(F)C(Br)CCC1

Computational Chemistry Data

TPSA 0
LogP 2.5691
H_Acceptors 0
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS02,GHS07
Signal Word : Danger	UN#: 1993
Class : 3	Packing Group : Ⅱ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362-P370+P378-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Fatty ring compounds Cyclopentane compounds

Key Words

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2-Bromo-1,1-difluorocyclopentane

CAS No. 2303705-25-9

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