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Structure of 2304635-53-6
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tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate features a boronate ester integrated into a strained azetidine ring, enabling efficient Suzuki-Miyaura coupling. The tetramethyl-substituted dioxaborolane enhances stability and reactivity under standard conditions, while the tert-butyl carbamate group provides convenient protection and orthogonal handling in synthetic sequences.
tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate serves as a stable, bench-ready boron building block for Suzuki-Miyaura coupling reactions. The azetidine core provides a strained heterocyclic scaffold relevant to medicinal chemistry, while the pinacol boronate ester enables reliable cross-coupling under mild conditions. It exhibits excellent functional group tolerance and facilitates efficient late-stage diversification in target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: