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Structure of 2306276-55-9
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Tert-butyl 8-oxo-2-azaspiro[5.5]undecane-2-carboxylate is a sterically encumbered spirocyclic scaffold featuring a ketone at C8 and a protected carboxylic acid at C2. This configuration enables direct functionalization at the azaspiro core, supporting rapid access to complex heterocycles in medicinal chemistry campaigns. The tert-butyl ester enhances solubility and stability under standard bench conditions.
Tert-butyl 8-oxo-2-azaspiro[5.5]undecane-2-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry applications, featuring a ketone at C8 and a protected amine at N2. The tert-butyl ester enables straightforward deprotection under mild acidic conditions, while the spirocyclic core provides conformational rigidity and enhanced metabolic stability. It functions effectively in standard functional group interconversions and supports diverse downstream transformations relevant to heterocycle-based drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: