4-Amino-N-methylphthalimide

Name: 4-Amino-N-methylphthalimide
Brand: ChemScene
Availability: InStock
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CAS No. 2307-00-8
Cat. No. CS-0076926
Purity≥98%
MDL No.MFCD00012081

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HazMat Fee

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 2307-00-8

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Description

4-Amino-N-methylphthalimide features a strategically positioned amino group and methylated phthalimide core, enabling selective conjugation in bioconjugation workflows. The electron-rich amine facilitates efficient coupling reactions, while the N-methyl substitution enhances metabolic stability and solubility under physiological conditions.

Application

4-Amino-N-methylphthalimide serves as a versatile building block in medicinal chemistry, enabling direct incorporation of both amino and phthalimide functionalities into target molecules. Its stability under standard reaction conditions and compatibility with common coupling protocols facilitate efficient synthesis of heterocyclic scaffolds and API intermediates. The N-methyl group enhances metabolic stability while maintaining reactivity for further derivatization via nucleophilic substitution or amidation reactions.

General Information

CAS No. 2307-00-8
Cat. No. CS-0076926
Purity ≥98%
MDL No. MFCD00012081
Storage RT, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₈N₂O₂
Molecular Weight 176.18
Synonym(s) None
SMILES O=C1C2=CC=C(N)C=C2C(=O)N1C

Computational Chemistry Data

TPSA 63.4
LogP 0.4946
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Other aromatic heterocycles compounds

General Reagents Organic General Reagents

Key Words

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4-Amino-N-methylphthalimide

CAS No. 2307-00-8

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