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Structure of 234445-61-5
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2-Isopropylthiazole-4-carboxylic acid features a thiazole core functionalized with a carboxylic acid at the 4-position and a sterically hindered isopropyl group at the 2-position. This combination imparts enhanced solubility and metabolic stability, enabling efficient incorporation into bioactive scaffolds for medicinal chemistry applications.
2-Isopropylthiazole-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of thiazole-based scaffolds prevalent in bioactive molecules. Its carboxylic acid functionality facilitates direct coupling reactions, while the isopropyl group enhances metabolic stability and modulates lipophilicity. The compound exhibits good bench stability and functional group tolerance, making it well-suited for iterative synthetic workflows and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: