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CS-W001157 4
Total: USD 88.00

3-Amino-3-oxopropanoic acid

  • CAS No. 2345-56-4

  • Cat. No. CS-0149950
  • Purity≥97%
  • MDL No.MFCD00154605

*For research and further manufacturing use only, not for direct human use.

3-Amino-3-oxopropanoic acid|CS-0149950

Structure of 2345-56-4

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General Information

  • CAS No. 2345-56-4
  • Cat. No. CS-0149950
  • Purity ≥97%
  • MDL No. MFCD00154605
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₅NO₃
  • Molecular Weight 103.08
  • Synonym(s) 3-Chloro-3-Oxopropanoic Acid
  • SMILES NC(CC(O)=O)=O

Description

3-Amino-3-oxopropanoic acid features a reactive α,β-unsaturated carbonyl system paired with a primary amine group, enabling direct conjugation in bioconjugation workflows. This bifunctional scaffold integrates readily into peptide and small-molecule architectures under mild conditions.

Application

3-Amino-3-oxopropanoic acid serves as a versatile building block in synthetic organic chemistry, enabling the construction of β-amino carbonyl systems and heterocyclic scaffolds. Its dual functionality—amine and carboxylate groups—facilitates efficient coupling reactions and participates in condensation pathways under mild conditions. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it a practical choice for peptide mimetics and medicinal chemistry campaigns.

Synthesis

  • Route1
    • null|null
      15159-48-5
    • ~%
    • In-stock
      3-Amino-3-oxopropanoic acid|CS-0149950
      2345-56-4

    References

    • Journal of the American Chemical Society, , vol. 106, # 16 p. 4814 - 4818
  • Route2
    • Ethyl 3-amino-3-oxopropanoate Tofacitinib Impurity|CS-0167588
      7597-56-0
    • ~%
    • In-stock
      3-Amino-3-oxopropanoic acid|CS-0149950
      2345-56-4

    References

    • Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy, , vol. 51, # 10 p. 1601 - 1616
  • Route3
    • null|null
      105-53-3
    • ~%
    • In-stock
      3-Amino-3-oxopropanoic acid|CS-0149950
      2345-56-4

    References

    • Chimica Therapeutica, , vol. 4, p. 120 - 126

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   80.39
  • LogP   -1.0536
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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