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Structure of 23669-79-6
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5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine serves as a protected nucleoside building block for solid-phase oligonucleotide synthesis. The dimethoxytrityl group at the 5'-position provides stable protection under acidic conditions while enabling efficient coupling and controlled chain elongation. This derivative ensures high fidelity during automated synthesis of DNA sequences containing uracil residues.
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine serves as a key building block in solid-phase oligonucleotide synthesis, enabling efficient 3'-to-5' chain elongation. The dimethoxytrityl group provides excellent protection at the 5'-hydroxyl, ensuring high coupling efficiency and ease of purification via trityl cation removal. Its stability under standard synthetic conditions and compatibility with various phosphoramidite coupling protocols make it a reliable choice for the synthesis of DNA sequences requiring uridine incorporation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: