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Structure of 240139-82-6
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2-Methoxy-5-(trifluoromethyl)phenylboronic acid features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the methoxy substituent improves solubility and modulates reactivity. This combination enables efficient coupling in Suzuki-Miyaura reactions under standard conditions.
2-Methoxy-5-(trifluoromethyl)phenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the methoxy substituent provides moderate electron-donating character and improved solubility. The boronic acid moiety exhibits excellent bench stability and compatibility with a broad range of reaction conditions, facilitating straightforward purification and integration into complex molecular architectures common in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P261-P264-P271-P280-P302+P352-P304+P340-P362-P403-P405-P501
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Lot numbers can be found on the outside label of a product: