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Structure of 262587-05-3
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1-Bromo-3-(difluoromethoxy)benzene features a strategically positioned difluoromethoxy group that enhances metabolic stability and modulates lipophilicity. This aryl bromide integrates readily into cross-coupling reactions, enabling efficient access to complex fluorinated aromatic scaffolds under standard conditions.
1-Bromo-3-(difluoromethoxy)benzene serves as a versatile aryl halide building block for palladium-catalyzed cross-coupling reactions, including Suzuki, Stille, and Negishi couplings. The difluoromethoxy group imparts enhanced metabolic stability and modulates electronic properties, making this compound valuable in the synthesis of fluorinated aromatic scaffolds relevant to medicinal chemistry and agrochemical research. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient, scalable transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: