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CS-W001157 4
Total: USD 88.00

4-Cyanopiperidine hydrochloride

  • CAS No. 240401-22-3

  • Cat. No. CS-0019876
  • Purity≥95%
  • MDL No.MFCD09037930
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Cyanopiperidine hydrochloride|CS-0019876

Structure of 240401-22-3

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Description

4-Cyanopiperidine hydrochloride offers a stable, moisture-tolerant platform for medicinal chemistry applications. The electron-deficient nitrile group enhances target engagement in kinase inhibition studies, while the protonated piperidine ring ensures solubility and bioavailability. This salt form facilitates handling and purification under standard bench conditions.

Application

4-Cyanopiperidine (hydrochloride) serves as a versatile building block in medicinal chemistry, enabling efficient access to nitrogen-containing heterocycles and bioactive scaffolds. The nitrile group provides a handle for nucleophilic transformations and downstream functionalization, while the piperidine core offers favorable physicochemical properties for drug-like molecules. Bench-stable and readily purified, it functions effectively in standard coupling and cyclization protocols.

General Information

  • CAS No. 240401-22-3
  • Cat. No. CS-0019876
  • Purity ≥95%
  • MDL No. MFCD09037930
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁ClN₂
  • Molecular Weight 146.62
  • Synonym(s) Piperidine-4-carbonitrile hydrochloride
  • SMILES N#CC1CCNCC1.[H]Cl

Computational Chemistry Data

  • TPSA   35.82
  • LogP   0.93138
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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