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Structure of 69478-75-7
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N,N-Dimethylpyrrolidin-3-amine delivers a sterically hindered nitrogen center ideal for catalytic applications. This bench-stable amine integrates readily into transition-metal complexes, enhancing reactivity in cross-coupling and C–H functionalization processes. The dimethyl substitution stabilizes the lone pair while maintaining solubility in polar aprotic solvents.
N,N-Dimethylpyrrolidin-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds through nucleophilic substitution and coupling reactions. Its tertiary amine functionality offers enhanced solubility and metabolic stability, while the pyrrolidine core provides conformational rigidity beneficial for target engagement. The dimethylamino group facilitates easy purification via ion-exchange chromatography and exhibits broad functional group tolerance under standard synthetic conditions, making it ideal for parallel synthesis campaigns and lead optimization workflows.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 2734
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Class : 8 (3)
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Packing Group : Ⅱ
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Hazard Statements : H226-H314
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: