Fmoc-N-methyl-(S)-3-Cyclobutylalanine

Name: Fmoc-N-methyl-(S)-3-Cyclobutylalanine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 2407819-94-5
Cat. No. CS-0439388
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Fmoc-N-methyl-(S)-3-Cyclobutylalanine|CS-0439388

Structure of 2407819-94-5

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Fmoc-N-methyl-(S)-3-cyclobutylalanine features a sterically hindered cyclobutyl group that enhances conformational rigidity in peptide synthesis. The N-methylated amine reduces hydrogen bonding potential, improving membrane permeability. This derivative integrates seamlessly into solid-phase workflows, offering enhanced stability and controlled backbone dynamics for bioactive peptide design.

Application

Fmoc-N-methyl-(S)-3-cyclobutylalanine serves as a valuable building block in peptide synthesis, offering a sterically constrained, hydrophobic side chain ideal for modulating peptide conformation and membrane permeability. The Fmoc group enables efficient N-terminal protection with orthogonal deprotection, while the N-methyl functionality enhances metabolic stability and reduces hydrogen-bonding potential. This derivative facilitates the incorporation of cyclobutyl motifs into peptidomimetics and bioactive scaffolds, supporting diverse applications in medicinal chemistry and drug discovery workflows.

General Information

CAS No. 2407819-94-5
Cat. No. CS-0439388
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₃H₂₅NO₄
Molecular Weight 379.45
Synonym(s) None
SMILES C(OC(N([C@@H](CC1CCC1)C(O)=O)C)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Computational Chemistry Data

TPSA 66.84
LogP 4.5107
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 6

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Fatty ring compounds Cyclobutane compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Alanine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Key Words

Fmoc-N-methyl-(S)-3-Cyclobutylalanine sigmaFmoc-N-methyl-(S)-3-Cyclobutylalanine manufacturerFmoc-N-methyl-(S)-3-Cyclobutylalanine priceFmoc-N-methyl-(S)-3-Cyclobutylalanine structureFmoc-N-methyl-(S)-3-Cyclobutylalanine SDSbuy Fmoc-N-methyl-(S)-3-CyclobutylalanineFmoc-N-methyl-(S)-3-Cyclobutylalanine supplierFmoc-N-methyl-(S)-3-Cyclobutylalanine usesFmoc-N-methyl-(S)-3-Cyclobutylalanine molecular weightprice of Fmoc-N-methyl-(S)-3-CyclobutylalanineFmoc-N-methyl-(S)-3-Cyclobutylalanine chemical name formula of Fmoc-N-methyl-(S)-3-Cyclobutylalanine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Fmoc-N-methyl-(S)-3-Cyclobutylalanine

CAS No. 2407819-94-5

Recommended Products