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Structure of 56423-63-3
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2-Bromopyrazine features a bromine substituent at the pyrazine ring's 2-position, enabling direct functionalization in cross-coupling reactions. This electron-deficient heterocycle integrates readily into pharmaceutical and agrochemical scaffolds, offering high reactivity under palladium catalysis. The molecule exhibits bench-stable handling with minimal moisture sensitivity, streamlining use in synthetic workflows.
2-Bromopyrazine serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. Its well-established reactivity facilitates the construction of biaryl and heteroaryl scaffolds common in pharmaceutical development. The bromine substituent offers excellent functional group tolerance and bench stability, simplifying purification and handling in multi-step syntheses.
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H302-H315-H318-H335
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Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P362-P370+P378-P403+P233-P403+P235-P405-P501
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Lot numbers can be found on the outside label of a product: